hrp0092p1-236 | Multisystem Endocrine Disorders | ESPE2019

Serum Endocan Levels as a Marker of Endothelial Dysfunction in Turner Syndrome and Correlation with Cardiac Findings

Gencay Ali Genco , Darendeliler Feyza , Nisli Kemal , Karaca Serra , Kardelen Asli Derya , Poyrazoglu Sükran , Bas Firdevs

Background: The most common reason for the increased mortality and morbidity in TS, which results from partial or complete deficiency of an X chromosome in a female, is acquired cardiovascular disease, which is the result of endothelial dysfunction that causes atherosclerosis. Endocan, an inflamatory marker, has been found elevated in several diseases with endothelial dysfunction (ED). There is no study of endocan levels in TS.Ob...

hrp0082p1-d1-199 | Reproduction | ESPE2014

Associations of Vascular Biomarkers and the Somatotrophic Axis with Carotid Ultrasound and Echocardiography Findings in Relation to Turner Arteriopathy

Ucar Ahmet , Oz Fahrettin , Bas Firdevs , Oflaz Huseyin , Nisli Kemal , Tugrul Melike , Darendeliler Feyza , Saka Nurcin , Poyrazoglu Sukran , Bundak Ruveyde

Background: Turner syndrome (TS) is associated with increased arterial stiffness. To date, factors associated with the ontogeny of Turner arteriopathy remain unclear.Objective and hypotheses: To assess the associations of vascular biomarkers and the somatotrophic axis with arterial stiffness indices, and left heart size, in normotensive ‘dipper’ TS.Method: Sixty-one patients with uncomplicated normotentensive &#1...